Michael Rosbash Research Group

Using Drosophila, his research connects circadian genes, regulation of gene expression, and the neural circuits that coordinate daily rhythms. The laboratory studies transcriptional and post-transcriptional mechanisms, including feedback involving clock proteins, and examines the functions of individual circadian neurons. Biochemical and genetic approaches help identify regulatory mechanisms and clock components. This offers a specific connection between molecular biology and neuroscience: understanding both the cellular timing machinery and how a brain uses that machinery to organize rhythmic activity.