Research labIndependently curated · Unclaimed

Carlos E. Crespo-Hernández Research Group

Case Western Reserve University
Location
Cleveland, OH
Department
Department of Chemistry
Recruiting
Availability unconfirmed
Updated
October 2, 2026

Research focus

photochemistryultrafast spectroscopytime-resolved spectroscopyphotobiologyphysical chemistrychemical dynamics

About the research

How do light-induced electronic excited-state dynamics in molecules control photochemical reactions relevant to therapy and imaging?

Read the full research overview

The group studies excited-state dynamics of UVA sensitizers and DNA analogues using time-resolved electronic spectroscopy and ultrafast methods to identify reaction pathways. Researchers measure ultrafast intersystem crossing rates and singlet oxygen yields in heavy-atom-free photosensitizers to evaluate photodynamic therapy efficacy. They synthesize and test small-molecule photosensitizers, photoswitches, and photonic materials, combining spectroscopy, HPLC, NMR, mass spectrometry, and microscopy for characterization. Computational chemistry and time-resolved instrumentation from femtoseconds to microseconds are used to link electronic relaxation mechanisms with observed chemical and cellular dynamics and photophysical behavior.

Selected publications

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People & alumni

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