Research focus
About the research
How can a short peptide be designed to interact with a cell membrane in a useful way?
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William Wimley investigates the structure, folding, and design of membrane proteins using peptide models. His lab combines traditional and combinatorial chemistry with high-throughput screening to develop membrane-spanning pores and peptides that recognize receptors associated with cancer. Potential applications include antibiotic design, drug delivery, and biosensors. The work connects fundamental membrane biophysics with the engineering of molecules that control or exploit interactions at cellular boundaries.
Selected publications
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