Research focus
About the research
A cancer biomarker is useful only if researchers understand what they are measuring.
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Rebecca Whelan studies the ovarian cancer marker CA125, including its structure and the sites recognized by antibodies. Her lab combines proteomics, microscale separations, bioinformatics, and affinity-reagent development to characterize biomarkers and improve recognition strategies. Research also develops aptamers against proteins and whole-cell targets, with potential uses in targeted delivery and simple detection devices. This connects analytical chemistry with the molecular details needed for better cancer measurement.
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