Frank Gupton Research Group

Through VCU’s Medicines for All Institute, his team redesigns routes for producing essential pharmaceutical ingredients, examining expensive starting materials, reaction steps, solvent use, and scale-up. VCU describes recent work on improving the synthesis of lenacapavir, alongside a broader record of process improvements for global-health medicines. The research moves from small laboratory batches toward reliable manufacturing methods. Its appeal lies in connecting detailed synthetic chemistry with a measurable practical goal: making established medicines easier and less costly to produce.